Ischemic Penumbra: MRI or PET
نویسندگان
چکیده
منابع مشابه
Sodium MRI of Core and Penumbra in ischemic stroke patients
Background and Purpose: Diffusionand perfusion-weighted imaging (DWI/PWI) of acute ischemic stroke can be used to identify the ischemic core (DWI) and to estimate the penumbral tissue (PWI-DWI mismatch) which is at risk of infarction but is potentially salvageable. MRI of sodium, a marker of ionic homeostasis that is disrupted after ischemia, within the lesion may be complementary by indicating...
متن کاملMeasurement of the ischemic penumbra with MRI: it's about time.
The idea that there exist 2 ischemic thresholds in the pathogenesis of cerebral infarction came from seminal microelectrode studies of the baboon cortex the late 1970s1,2 that measured the effects of progressive reductions in cerebral blood flow (CBF). These studies described a level of CBF reduction that led to cessation of cortical evoked responses in the absence of terminal increases in extr...
متن کاملThe cerebral ischemic penumbra.
When neuronal activity is suppressed by ischemia of sufficient severity, maintained for a long enough period of time, permanent clinical deficit can be accompanied by radiographic signs of cerebral infarction and histological evidence of ischemic damage. Recent work suggests that this is not an all-ornone event. Between the most densely ischemic region and the more normally perfused brain, an i...
متن کاملTargeting the ischemic penumbra.
BACKGROUND In the last 3 decades, and from a therapeutic point of view, the classical concept of ischemic penumbra based on hemodynamic and electrophysiological parameters has loosened up the rigidity of therapeutic windows in acute stroke management. Thirty years later, the ischemic penumbra is an evolved concept that presents more applications. Thus, the ischemic penumbra is a diagnostic targ...
متن کاملMRI Measurement of Ischemic Brain Penumbra Using an Inelastic Collision Model
Introduction: Multi-parametric MRI analysis of the ischemic lesions of stroke patients demonstrates inhomogeneities in the degree of ischemic injury and recovery potential [1]. Experimental and clinical studies indicate that the likelihood for progression to infarction in the penumbra of physiologically impaired but potentially salvageable tissue surrounding the central core of focal cerebral i...
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ژورنال
عنوان ژورنال: Stroke
سال: 2003
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000092397.46952.1f